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Invitrogen
C/EBP delta Polyclonal Antibody
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C/EBP delta Antibody (PA5-30262) in ChIP
Cell death & disease 2023 -
Fig. 6 CEBPD positively regulated ECM-mediated EGFR/PI3K pathway activity, and important genes involved in the pathway and invasion capacity, by directly binding to the promotors of key genes in ECM. A WB results showing the protein levels of CEBPD and key transducers of the EGFR/PI3K pathway, especially phosphorylated EGFR, ERK1/2, AKT, mTOR, STAT3, and essential genes for the invasion capacity, after CEBP... View More
Product Details
PA5-30262
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Full length human C/EBP delta Recombinant protein.
Conjugate
Form
Liquid
Concentration
0.58 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2547736
Product Specific Information
Recommended positive controls: HeLa, 3T3-L1.
Predicted reactivity: Mouse (85%), Rat (86%), Bovine (85%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
C/EBP delta are CCAAT enhancer binding proteins (CEBPs), a family of transcription factors that all contain a highly conserved, basic-leucine zipper domain at the C-terminus that is involved in dimerization and DNA binding. At least six members of the family have been isolated and characterized to date (CEBP alpha to CEBP zeta). CEBPD is a leucine zipper (LZ) DNA-binding protein that regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. CEBPD is an important transcriptional activator in the regulation of genes involved in immune and inflammatory responses and has been reported to possess many tumor suppressor-like properties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: C EBP; C/EBP delta; C/EBP-related protein 3; CCAAT/enhancer binding protein (C/EBP), delta; CCAAT/enhancer-binding protein delta; NF-IL6-beta; Nuclear factor NF-IL6-beta
Gene Aliases: C/EBP-delta; CEBPD; CELF; CRP3; NF-IL6-beta
UniProt ID: (Human) P49716, (Mouse) Q00322
Entrez Gene ID: (Human) 1052, (Mouse) 12609
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
protein binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein homodimerization activity
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity
hematopoietic progenitor cell differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
fat cell differentiation
positive regulation of osteoblast differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
inner ear development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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