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Immunogen sequence: MSELTKELME LVWGTKSSPG LSDTIFCRWT QGFVFSESEG SALEQFEGGP CAVIAPVQAF LLKKLLFSSE KSSWRDCSEE EQKELLCHTL CDILESACCD HSGS
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.
The protein encoded by this gene contains a caspase-associated recruitment domain and may function in apoptosis. It has been identified as a tumor suppressor in lung and gastric cancers, and a polymorphism in the gene may be associated with gastric cancer risk. Alternative splicing of this gene results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CARD-containing protein; caspase recruitment domain containing pro-apoptotic protein; caspase recruitment domain containing protein; Dermal papilla-derived protein 5; Deubiquitinating enzyme MINDY-3; family with sequence similarity 188, member A; MINDY lysine 48 deubiquitinase 3; Protein CARP; protein FAM188A; RP11-394I23.1; Ubiquitin carboxyl-terminal hydrolase MINDY-3
Gene Aliases: 1810041E18Rik; 2310047O13Rik; 5830410F13Rik; AI447827; AW111958; C10orf97; CARP; DERP5; FAM188A; MINDY3; MST126; MSTP126; My042; RGD1309605
UniProt ID: (Human) Q9H8M7, (Mouse) Q9CV28
Entrez Gene ID: (Human) 80013, (Mouse) 66960, (Rat) 291320
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