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Immunogen sequence: HRAYWAEQQS RLPLPLMELM ENEALEILTK ALRSYQLGIG RDHFLTKELQ RYIEGLKKRR SKRLYVN
Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for a distribution of the CatSper complex in linear quadrilateral nanodomains along the flagellum, maximizing fertilization inside the mammalian female reproductive tract. Together with EFCAB9, associates with the CatSper channel pore and is required for the two-row structure of each single CatSper channel. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cation channel sperm-associated auxiliary subunit zeta; CatSper-zeta; Testis-expressed protein 40
Gene Aliases: C11orf20; CATSPERZ; TEX40
UniProt ID: (Human) Q9NTU4
Entrez Gene ID: (Human) 25858
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