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Immunogen sequence: LSPLLSVTSF RRFYRGDSPT DSQKDMIEIP LPPWQERTDE SIETKRARLL YESRKRGMLE NCILL
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 100%.
SDHAF2, also named asC11orf79, SDHAF2 and SDH5, is a mitochondrial protein needed for the flavination of a succinate dehydrogenase complex subunit required for activity of the complex. SDHAF2 has been shown to be mutated in patients with paragangliomas, also known as familial non-chromaffin paragangliomas type 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hSDH5; SDH assembly factor 2; SDHAF2; Succinate dehydrogenase assembly factor 2, mitochondrial; succinate dehydrogenase subunit 5, mitochondrial
Gene Aliases: C11orf79; PGL2; SDH5; SDHAF2
UniProt ID: (Human) Q9NX18
Entrez Gene ID: (Human) 54949
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