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Predicted Reactivity: Mouse (90%), Rat (90%), Zebrafish (80%), Xenopus laevis (84%), Dog (100%), Pig (98%), Bovine (100%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing (PubMed:23904267). [UniProt]
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: asunder spermatogenesis regulator; asunder, spermatogenesis regulator homolog (Drosphila); Cell cycle regulator Mat89Bb homolog; Germ cell tumor 1; Integrator complex subunit 13; Protein asunder homolog; Sarcoma antigen NY-SAR-95; spermatogenesis associated 30
Gene Aliases: ASUN; C12orf11; GCT1; INTS13; Mat89Bb; NET48; SPATA30
UniProt ID: (Human) Q9NVM9
Entrez Gene ID: (Human) 55726
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