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Product Details
PA5-66622
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human C13orf15. Recombinant protein control fragment (Product #RP-107280).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2664759
Product Specific Information
Immunogen sequence: LSDALCEFDAV LADFASPFHE RHFHYEEHLE RMK
Highest antigen sequence identity to the following orthologs - mouse 94%, rat 94%.
Target Information
Modulates the activity of cell cycle-specific kinases. Enhances CDK1 activity. May contribute to the regulation of the cell cycle. May inhibit growth of glioma cells by promoting arrest of mitotic progression at the G2/M transition. Fibrogenic factor contributing to the pathogenesis of renal fibrosis through fibroblast activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Regulator of cell cycle RGCC; Response gene to complement 32 protein; RGC-32
Gene Aliases: bA157L14.2; C13orf15; RGC-32; RGC32; RGCC
UniProt ID: (Human) Q9H4X1
Entrez Gene ID: (Human) 28984
negative regulation of exit from mitosis
negative regulation of endothelial cell proliferation
positive regulation of extracellular matrix constituent secretion
complement activation
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
negative regulation of cell proliferation
positive regulation of gene expression
positive regulation of epithelial to mesenchymal transition
negative regulation of angiogenesis
positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
activation of protein kinase activity
positive regulation of collagen biosynthetic process
negative regulation of blood vessel endothelial cell migration
positive regulation of mitotic nuclear division
positive regulation of transcription from RNA polymerase II promoter
negative regulation of cytokine secretion
positive regulation of cytokine secretion
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of stress fiber assembly
positive regulation of cell cycle arrest
cellular response to hypoxia
mitotic cell cycle arrest
fibroblast activation
negative regulation of fibroblast growth factor production
positive regulation of extracellular matrix assembly
negative regulation of mitotic cell cycle phase transition
negative regulation of cell-cell adhesion mediated by cadherin
positive regulation of endothelial cell apoptotic process
positive regulation of DNA biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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