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Product Details
H00055148-B01P
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
C14orf130 (NP_060578.2, 1 a.a. approximately 274 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MIQCVVCEDW FHGRHLGAIP PESGDFQEMV CQACMKRCSF LWAYAAQLAV TKISTEDDGL VRNIDGIGDQ EVIKPENGEH QDSTLKEDVP EQGKDDVREV KVEQNSEPCA GSSSESDLQT VFKNESLNAE SKSGCKLQEL KAKQLIKKDT ATYWPLNWRS KLCTCQDCMK MYGDLDVLFL TDEYDTVLAY ENKGKIAQAT DRSDPLMDTL SSMNRVQQVE LICEYNDLKT ELKDYLKRFA DEGTVVKRED IQQFFEEFQS KKRRRVDGMQ YYCS
Target Information
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway, recognizes and binds to proteins bearing specific amino-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7; RING-type E3 ubiquitin transferase UBR7
Gene Aliases: 5730410I19Rik; AA589405; AW557761; C14orf130; RGD1359144; UBR7
UniProt ID: (Human) Q8N806, (Mouse) Q8BU04
Entrez Gene ID: (Human) 55148, (Rat) 314399, (Mouse) 66622
molecular_function
zinc ion binding
ligase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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