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Immunogen sequence: RQSELEPVVS LVDVLEEDEE LENEACAVLG GSDSEKCSYS QGSVKRQALY ACSTCTPEGE EPAGICLACS YECHGSHKLF ELYTKRNFRC DCGNSKFKNL ECKLLPDKAK VNSGNKYNDN FFGLYCICKR PYPDPEDEI
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 96%.
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway, recognizes and binds to proteins bearing specific amino-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7; RING-type E3 ubiquitin transferase UBR7
Gene Aliases: C14orf130; UBR7
UniProt ID: (Human) Q8N806
Entrez Gene ID: (Human) 55148
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