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Immunogen sequence: MADTLESSL EDPLRSFVRV LEKRDGTVLR LQQYSSGGVG CVVWDAAIVL SKYLETPEFS GDGAHALSRR SVLELGSGTG AVGLMAATLG ADVVVTDLEE LQDLLKMNIN MNKHLVTGSV QAKGGRNRRL SFSTRLHTDG RLHIL (1-144 aa encoded by BC105118)
C14orf138, also named as VCPKMT or METTL21D, is 229 amino acid protein, which belongs to the methyltransferase superfamily. C14orf138 localizes in the cytoplasm and interacts with ALKBH6. C14orf138 as a Protein-lysine N-methyltransferase that specifically trimethylates 'Lys-315' of VCP/p97; this modification may decrease VCP ATPase activity. C14orf138 exists as five isoforms. The calculated molecular weight of C14orf138 is 26 kDa, but we always detected a 46-50 kDa protein by western blot.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: methyltransferase like 21D; Methyltransferase-like protein 21D; Protein N-lysine methyltransferase METTL21D; valosin containing protein lysine (K) methyltransferase; Valosin-containing protein lysine methyltransferase; VCP lysine methyltransferase; VCP-KMT
Gene Aliases: C14orf138; METTL21D; VCP-KMT; VCPKMT
UniProt ID: (Human) Q9H867
Entrez Gene ID: (Human) 79609
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