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Proteintech
C17orf85 Polyclonal Antibody
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Product Details
24384-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
C17orf85 Fusion Protein Ag20021 (16-340 aa encoded by BC148856)
Conjugate
Form
Liquid
Concentration
0.28 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SNSWKRRYH SRRIQRDVIK KRALIGDDVG LTSYKHRHSG LVNVPEEPIE EEEEEEEEEE EEEEEDQDMD ADDRVVVEYH EELPALKQPR ERSASRRSSA SSSDSDEMDY DLELKMISTP SPKKSMKMTM YADEVESQLK NIRNSMRADS VSSSNIKNRI GNKLPPEKFA DVRHLLDEKR QHSRPRPPVS STKSDIRQRL GKRPHSPEKA FSSNPVVRRE PSSDVHSRLG VPRQDSKGLY ADTREKKSGN LWTRLGSAPK TKEKNTKKVD HRAPGAEEDD SELQRAWGAL IKEKEQSRQK KSRLDNLPSL QIEVSRESSS GSEAES (16-340 aa encoded by BC148856)
Target Information
Associates with NCBP1/CBP80 to form an alternative cap-binding complex (CBC) which plays a key role in mRNA export. NCBP3 serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with NCBP3 does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress situations such as virus infections and the NCBP3 activity is critical to inhibit virus growth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CTD-3195I5.1; CTD-3195I5.5; Nuclear cap-binding protein subunit 3; Protein ELG
Gene Aliases: C17orf85; ELG; HSA277841; NCBP3
UniProt ID: (Human) Q53F19
Entrez Gene ID: (Human) 55421
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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