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Product Details
H00114899-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
C1QTNF3 (NP_112207, 1 a.a. approximately 246 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.35 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MLWRQLIYWQ LLALFFLPFC LCQDEYMESP QTGGLPPDCS KCCHGDYSFR GYQGPPGPPG PPGIPGNHGN NGNNGATGHE GAKGEKGDKG DLGPRGERGQ HGPKGEKGYP GIPPELQIAF MASLATHFSN QNSGIIFSSV ETNIGNFFDV MTGRFGAPVS GVYFFTFSMM KHEDVEEVYV YLMHNGNTVF SMYSYEMKGK SDTSSNHAVL KLAKGDEVWL RMGNGALHGD HQRFSTFAGF LLFETK
Target Information
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Multiple isoforms of human CTRP3 have been reported. It has been suggested that CTRP3 may play a role in skeletal development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cartonectin; Collagenous repeat-containing sequence 26 kDa protein; collagenous repeat-containing sequence of 26-kDa; Complement C1q tumor necrosis factor-related protein 3; CORS26; Secretory protein CORS26
Gene Aliases: C1ATNF3; C1QTNF3; CORCS; CORS; CORS-26; CORS26; CTRP3; UNQ753/PRO1484
UniProt ID: (Human) Q9BXJ4
Entrez Gene ID: (Human) 114899
cellular triglyceride homeostasis
negative regulation of NF-kappaB import into nucleus
fat cell differentiation
negative regulation of gluconeogenesis
positive regulation of cytokine secretion
negative regulation of inflammatory response
positive regulation of adiponectin secretion
protein trimerization
negative regulation of monocyte chemotactic protein-1 production
negative regulation of interleukin-6 secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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