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Together with SMCHD1, involved in chromosome X inactivation in females by promoting the compaction of heterochromatin (PubMed:23542155). Also able to repress the ligand-induced transcriptional activity of retinoic acid receptor alpha (RARA), possibly through direct recruitment of histone deacetylases (PubMed:17455211). [UniProt]
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Protein Aliases: HBiX1; HP1-binding protein enriched in inactive X chromosome protein 1; Ligand-dependent nuclear receptor-interacting factor 1; receptor interacting factor 1; Receptor-interacting factor 1
Gene Aliases: 2010012G17Rik; 4933421E11Rik; AI450568; C1orf103; LRIF1; RGD1306520; RIF1
UniProt ID: (Human) Q5T3J3, (Mouse) Q8CDD9
Entrez Gene ID: (Human) 55791, (Rat) 310775, (Mouse) 321000
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