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Invitrogen
C1orf146 Polyclonal Antibody
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Product Details
PA5-31672
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human C1orf146. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.81 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2549145
Product Specific Information
Recommended positive controls: 293T, Raji.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The C1orf146 gene, also known as FAM213A, encodes a protein involved in antioxidative and anti-inflammatory processes within the cell. Located on chromosome 1, FAM213A (family with sequence similarity 213 member A) has been implicated in several critical cellular functions, including the regulation of reactive oxygen species (ROS) and modulation of inflammatory responses. The protein encoded by C1orf146 is known to interact with peroxiredoxins, which are crucial for protecting cells from oxidative damage. Research has shown that alterations in FAM213A expression can affect cellular susceptibility to oxidative stress and may play a role in the pathogenesis of various diseases, including cancer and inflammatory disorders.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein SPO16 homolog; RP11-163M2.4; Synaptonemal complex reinforcing element
Gene Aliases: C1orf146; SCRE; SPO16
UniProt ID: (Human) Q5VVC0
Entrez Gene ID: (Human) 388649
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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