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Product Details
BS-9219R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human C1orf149.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The screening of cDNA expression libraries from human tumors with serum antibody (SEREX) has proven to be a powerful method for identifying the repertoire of tumor antigens recognized by the immune system of cancer patients, referred to as the cancer immunome. In this regard, cancer/testis (CT) antigens are of particular interest because of their immunogenicity and restricted expression patterns. Synovial sarcomas are striking with regard to CT antigen expression, however, highly expressed in sarcoma, CT antigens do not induce frequent humoral immune responses in sarcoma patients. Sera from two patients were used to immunoscreen cDNA libraries from two synovial sarcoma cell lines and normal testis, resulting in the identification of 113 distinct antigens.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CDABP0189; centromere protein 28; Chromatin modification-related protein MEAF6; Esa1-associated factor 6 homolog; Esa1p-associated factor 6 homolog; FLJ11730; MYST/Esa1-associated factor 6; Protein EAF6 homolog; RP3-423B22.2; Sarcoma antigen NY-SAR-91
Gene Aliases: 2310005N01Rik; 2810036M01Rik; C1orf149; CENP-28; EAF6; MEAF6; NY-SAR-91; RGD1310440
UniProt ID: (Human) Q9HAF1, (Mouse) Q2VPQ9
Entrez Gene ID: (Human) 64769, (Mouse) 70088, (Rat) 362594
transcription, DNA-templated
regulation of transcription, DNA-templated
histone H2A acetylation
histone H4-K5 acetylation
histone H4-K8 acetylation
histone H4-K12 acetylation
histone H4-K16 acetylation
histone H3-K14 acetylation
regulation of signal transduction by p53 class mediator
chromatin modification
biological_process
Performance Guarantee
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