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Fabgennix
C1orf187 Polyclonal Antibody, FITC
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Product Details
DRAX-FITC
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Chicken,
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 300-330 on C terminal region of Human Draxin protein.Region:NNKCFDDCMC VEGLRCYAKF HRNRRVTRRK
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dorsal inhibitory axon guidance protein; Dorsal repulsive axon guidance protein; Draxin; FLJ34999; MGC117222; Neucrin; neural tissue-specific cysteine-rich protein
Gene Aliases: 2610109H07Rik; AGPA3119; BOS_15828; C1orf187; DRAXIN; neucrin; PSEC0258; UNQ3119; UNQ3119/PRO10268
UniProt ID: (Bovine) P0C8S2, (Chicken) B6ZI38, (Human) Q8NBI3, (Mouse) Q6PAL1
Entrez Gene ID: (Bovine) 506110, (Chicken) 419492, (Human) 374946, (Rat) 691317, (Mouse) 70433
axon guidance
Wnt signaling pathway
dorsal spinal cord development
commissural neuron differentiation in spinal cord
forebrain development
negative regulation of canonical Wnt signaling pathway
negative regulation of axon extension
negative regulation of neuron apoptotic process
multicellular organism development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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