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Product Details
27846-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
C22orf25 Fusion Protein Ag27127 (1-276 aa encoded by BC041339)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MCIIFFKFD PRPVSKNAYR LILAANRDEF YSRPSKLADF WGNNNEILSG LDMEEGKEGG TWLGISTRGK LAALTNYLQP QLDWQARGRG ELVTHFLTTD VDSLSYLKKV SMEGHLYNGF NLIAANLSTA KGDVICYYGN RGEPDPIVLT PGTYGLSNAL LETPWRKLCF GKQLFLEAVE RSQALPKDVL IASLLDVLNN KEAQLPDPAI EDQGGEYVQP MLSKYAAVCV RCPGYGTRTN TIILVDADGH VTFTERSMMD KDLSHWETRT YEFTLQS (1-276 aa encoded by BC041339)
Target Information
This gene belongs to the transport and Golgi organization family, whose members are predicted to play roles in secretory protein loading in the endoplasmic reticulum. Depletion of this gene in Drosophila S2 cells causes fusion of the Golgi with the ER. In mouse tissue culture cells, this protein co-localizes with a mitochondrially targeted mCherry protein and displays very low levels of co-localization with Golgi and peroxisomes. Allelic variants of this gene are associated with rhabdomyolysis, metabolic crises with encephalopathy, and cardiac arrhythmia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Ser/Thr-rich protein T10 in DGCR region; Transport and Golgi organization 2 homolog; Transport and Golgi organization protein 2 homolog
Gene Aliases: C22orf25; D16H22S680E; MECRCN; T10; TANGO2
UniProt ID: (Human) Q6ICL3, (Mouse) P54797
Entrez Gene ID: (Human) 128989, (Mouse) 27883
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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