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          • Primary Antibodies ›
          • SMDT1 Antibodies

          Bioss

          C22orf32 Polyclonal Antibody

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          Cite C22orf32 Polyclonal Antibody

          Product Details

          BS-15136R

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:400
          -

          Immunohistochemistry (Frozen) (IHC (F))

          1:100-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:100-1:500
          -

          ELISA (ELISA)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          KLH conjugated synthetic peptide derived from human C22orf32, amino acids 1-60.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

          Contains

          0.02% ProClin 300

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria (PubMed:24231807, PubMed:26774479, PubMed:27099988). Required to bridge the calcium-sensing proteins MICU1 and MICU2 with the calcium-conducting subunit MCU (PubMed:24231807). Plays a central role in regulating the uniplex complex response to intracellular calcium signaling (PubMed:27099988). Acts by mediating activation of MCU and retention of MICU1 to the MCU pore, in order to ensure tight regulation of the uniplex complex and appropriate responses to intracellular calcium signaling (PubMed:27099988).

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Essential MCU regulator, mitochondrial; single-pass membrane protein with aspartate-rich tail 1; Single-pass membrane protein with aspartate-rich tail 1, mitochondrial; UPF0466 protein C22orf32 homolog, mitochondrial; UPF0466 protein C22orf32, mitochondrial

          View more View less

          Gene Aliases: 1500032L24Rik; C22orf32; DDDD; dJ186O1.1; EMRE; RGD1311310; SMDT1

          View more View less

          UniProt ID: (Human) Q9H4I9, (Mouse) Q9DB10

          View more View less

          Entrez Gene ID: (Human) 91689, (Rat) 315166, (Mouse) 69029

          View more View less

          Function(s)
          protein binding molecular_function
          Process(es)
          mitochondrial calcium ion transport calcium ion transmembrane import into mitochondrion mitochondrial calcium ion homeostasis transport ion transport calcium ion transport
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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