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Immunogen sequence: MDDADPEER NYDNMLKMLS DLNKDLEKLL EEMEKISVQA TWMAYDMVVM RTNPTLAESM RRLEDAFVNC KEEMEKNWQE LLHETKQRL (1-88 aa encoded by BC127859)
Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for chromosome loading of the central element-specific SCS proteins, and for initiating synapsis between homologous chromosomes. Chromosome loading appears to require SYCP1. Required for fertility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Synaptonemal complex central element protein 3; Testis highly expressed gene 2 protein; testis highly expressed protein 2; Testis-specific expressed protein 2; THEG-2; TSEG-2
Gene Aliases: 1700007E06Rik; C22orf41; SYCE3; THEG2; TSEG-2; TSEG2
UniProt ID: (Human) A1L190, (Mouse) B5KM66
Entrez Gene ID: (Human) 644186, (Mouse) 75459
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