Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MALAARLLP QFLHSRSLPC GAVRLRTPAV AEVRLPSATL CYFCRCRLGL GAALFPRSAR ALAASALPAQ GSRWPVLSSP GLPAAFASFP ACPQRSYSTE EKPQQHQKTK MIVLGFSNPI NWVRTRIKAF LIWAYFDKEF SITEFSEGAK QAFAHVSKLL SQCKFDLLEE LVAKEVLHAL KEKVTSLPDN HKNALAANID EIVFTSTGDI SIYYDEKGRK FVNILMCFWY LTSANIPSET LRGASVFQVK LGNQNVETKQ LLSASYEFQR EFTQGVKPDW TIARIEHSKL LE (1-291 aa encoded by BC017959)
Promotes sorting of SMDT1/EMRE in mitochondria by ensuring its maturation. Interacts with the transit peptide region of SMDT1/EMRE precursor protein in the mitochondrial matrix, leading to protect it against protein degradation by YME1L1, thereby ensuring SMDT1/EMRE maturation by the mitochondrial processing peptidase (PMPCA and PMPCB).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: m-AAA protease-interacting protein 1, mitochondrial; Matrix AAA peptidase-interacting protein 1; uncharacterized protein C2orf47 homolog, mitochondrial
Gene Aliases: AA409999; C2orf47; C78988; MAIP1
UniProt ID: (Mouse) Q8BHE8, (Human) Q8WWC4
Entrez Gene ID: (Mouse) 68115, (Human) 79568
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