Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
C4orf49 Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
22569-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
C4orf49 Fusion Protein Ag16552 (1-240 aa encoded by BC104174)
Conjugate
Form
Liquid
Concentration
0.43 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MYLRRAVSK TLALPLRAPP NPAPLGKDAS LRRMSSNRFP GSSGSNMIYY LVVGVTVSAG GYYAYKTVTS DQAKHTEHKT NLKEKTKAEI HPFQGEKENV AETEKASSEA PEELIVEAEV VDAEESPSAT VVVIKEASAC PGHVEAAPET TAVSAETGPE VTDAAARETT EVNPETTPEV TNAALDEAVT IDNDKDTTKN ETSDEYAELE EENSPAESES SAGDDLQEEA SVGSEAASAQ G (1-240 aa encoded by BC104174)
Target Information
MGARP plays a role in the trafficking of mitochondria along microtubules. It regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia. It participates in the translocation of TRAK2/GRIF1 from the cytoplasm to the mitochondrion. It also plays a role in steroidogenesis through maintenance of mitochondrial abundance and morphology.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: CESP-1; Corneal endothelium-specific protein 1; Hypoxia up-regulated mitochondrial movement regulator protein; Mitochondria-localized glutamic acid-rich protein; Ovary-specific acidic protein; Protein MGARP
Gene Aliases: 4930583H14Rik; AI195347; C4orf49; CESP-1; CESP1; GS3582; HUMMR; MGARP; OSAP; Qsap
UniProt ID: (Human) Q8TDB4, (Mouse) Q8VI64
Entrez Gene ID: (Human) 84709, (Mouse) 67749
protein targeting to mitochondrion
anterograde axonal transport
retrograde axonal transport
positive regulation of mitochondrion organization
axonal transport of mitochondrion
cellular response to steroid hormone stimulus
cellular response to hypoxia
cellular response to gonadotropin-releasing hormone
regulation of mitochondrion organization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support