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Invitrogen
C9ORF72 Polyclonal Antibody
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FIGURE: 1 / 4
C9ORF72 Antibody (PA5-114361) in WB
Western blot analysis of C9ORF72 in the following samples: Lane 1: human placenta tissue lysates, Lane 2: human U2OS whole cell lysates, Lane 3: human PC-3 whole cell lysates, Lane 4: human K562 whole cell lysates, Lane 5: human HeLA whole cell lysates, Lane 6: human A431 whole cell lysates, Lane 7: human A549 whole cell lysates. Samples consisting of 50 µg (reducing conditions) of protein was separated with 5-20% SDS-PAGE gel (70V, Stacking gel; 90V, Resolving gel; 2-3 hrs.), transferred to a Nitrocellulose membrane (150mA, 50-90 min) and... View More
Product Details
PA5-114361
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence of human C9ORF72 (APKTEQVLLSDGEITFLANHTLNGEILR).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2884818
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human placenta tissue, human U2OS whole cell, human PC-3 whole cell, human K562 whole cell, human Hela whole cell, human A431 whole cell, human A549 whole cell, rat brain tissue, rat liver tissue, rat C6 whole cell, mouse liver tissue, mouse HEPA1-6 whole cell. Flow: U20S cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
C9orf72 may play a role in endosomal trafficking and autophagy. It is known to interact with HNRNPA1, HNRNPA2B1, UBQLN2, and small Rab GTPSases. C9orf72 localizes in the nucleus, cytoplasm, endosome, lysosome, and autophagosome. Mutations in this gene can result in frontotemporal dementia and/or amyotrophic lateral sclerosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Guanine nucleotide exchange factor C9orf72; Guanine nucleotide exchange factor C9orf72 homolog; protein C9orf72 homolog
Gene Aliases: AI840585; ALSFTD; C9orf72; DENND9; DENNL72; FTDALS; FTDALS1
UniProt ID: (Mouse) Q6DFW0, (Human) Q96LT7, (Rat) Q66HC3
Entrez Gene ID: (Mouse) 73205, (Human) 203228, (Rat) 313155
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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