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Antibody detects endogenous levels of total C9orf142.
The protein encoded by this gene plays a role in the nonhomologous end joining (NHEJ) pathway of DNA double-strand break repair. The encoded protein may function to stabilize the Ku70/Ku80 heterodimer to facilitate the assembly and maintain the stability of the NHEJ complex.
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Protein Aliases: Paralog of XRCC4 and XLF; Protein PAXX; uncharacterized protein C9orf142 homolog; XRCC4-like small protein
Gene Aliases: C9orf142; D930050G13Rik; PAXX; XLS
UniProt ID: (Mouse) Q8K0Y7, (Human) Q9BUH6
Entrez Gene ID: (Mouse) 227622, (Human) 286257, (Rat) 296565
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