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Bioss
C9orf7 Polyclonal Antibody
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Product Details
BS-15339R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human C9orf7, amino acids 41-130.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Transmembrane protein which mediates synaptic endocytosis and fitness-based cell culling. In response to different stimulus strengths, controls two major modes of synaptic vesicle (SV) retrieval in hippocampal neurons; Clathrin- mediated endocytosis (CME) in response to mild stimulation and activity-dependent bulk endocytosis (ADBE) in response to strong stimulation (By similarity). In cytotoxic T-lymphoocytes (CTLs) facilitates calcium-dependent endocytosis of cytotoxic granules at the immuno synapse (By similarity). Different isoforms work as fitness fingerprints in 'loser' and 'winner' cells and thereby mediate win/lose decisions as part of the cell competition process.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Calcium channel flower domain-containing protein 1; Calcium channel flower homolog; likely ortholog of H. sapiens chromosome 9 open reading frame 7 (C9orf7)
Gene Aliases: 5930434B04Rik; C9orf7; CACFD1; D9S2135; FLOWER; mFwe; PSEC0107; PSEC0248; RGD1311501; UNQ3071/PRO9903
UniProt ID: (Human) Q9UGQ2, (Rat) D4A9I3, (Mouse) Q8BG21
Entrez Gene ID: (Human) 11094, (Rat) 296599, (Mouse) 381356
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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