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Proteintech
CA11 Polyclonal Antibody
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Product Details
15435-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CA11 Fusion Protein Ag7712 (12-328 aa encoded by BC002662)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: ALVLWAALG AAAHIGPAPD PEDWWSYKDN LQGNFVPGPP FWGLVNAAWS LCAVGKRQSP VDVELKRVLY DPFLPPLRLS TGGEKLRGTL YNTGRHVSFL PAPRPVVNVS GGPLLYSHRL SELRLLFGAR DGAGSEHQIN HQGFSAEVQL IHFNQELYGN FSAASRGPNG LAILSLFVNV ASTSNPFLSR LLNRDTITRI SYKNDAYFLQ DLSLELLFPE SFGFITYQGS LSTPPCSETV TWILIDRALN ITSLQMHSLR LLSQNPPSQI FQSLSGNSRP LQPLAHRALR GNRDPRHPER RCRGPNYRLH VDGVPHGR (12-328 aa encoded by BC002662 )
Target Information
Carbonic Anhydrase XI (CA11, CA XI) is a member of the carbonic anhydrases (CAs) family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Carbonic Anhydrase XI participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. Further, Carbonic Anhydrase XI show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CA-RP II; CA-RP XI; CA-XI; carbonic anhydrase XI; Carbonic anhydrase-related protein 11; Carbonic anhydrase-related protein 2; carbonic anhydrase-related protein XI; carbonic anhydrase-related XI protein; CARP XI; CARP-2
Gene Aliases: CA11; CAR-XI; Car11; CARP2; CARPX1; UNQ211/PRO237
UniProt ID: (Human) O75493, (Mouse) O70354
Entrez Gene ID: (Human) 770, (Rat) 308588, (Mouse) 12348
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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