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Invitrogen
CABC1 Polyclonal Antibody
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CABC1 Antibody (PA5-106518) in IHC (P)
Immunohistochemistry analysis of CABC1 in rat kidney tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with CABC1 polyclonal antibody (Product # PA5-106518) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-106518
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human COQ8A(Accession Q8NI60), corresponding to amino acid residues S303-R353.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2854187
Product Specific Information
Antibody detects endogenous levels of total ADCK3.
Target Information
ADCK3 serine/threonine kinase is a mitochondrial protein similar to yeast ABC1 that is a member of the ADCK family. CABC1 encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: aarF domain containing kinase 3; aarF domain-containing protein kinase 3; atypical kinase ADCK3, mitochondrial; Atypical kinase COQ8A, mitochondrial; Chaperone activity of bc1 complex-like; chaperone activity of bc1 complex-like, mitochondrial; chaperone, ABC1 activity of bc1 complex homolog; chaperone, ABC1 activity of bc1 complex like; Chaperone-ABC1-like; Coenzyme Q protein 8A; coenzyme Q8 homolog
Gene Aliases: 4632432J16Rik; ADCK3; AI462003; ARCA2; CABC1; COQ10D4; COQ8; COQ8A; mKIAA0451; PP265; SCAR9
UniProt ID: (Rat) Q5BJQ0, (Mouse) Q60936, (Human) Q8NI60
Entrez Gene ID: (Rat) 360887, (Mouse) 67426, (Human) 56997
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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