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Product Details
OSC00258W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from aa region 990-1040 of mouse CACNA1B conjugated to blue carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: CACNA1B.
Target Information
The expression of multiple classes of voltage dependent calcium channels (VDCCs) allows neurons to tailor calcium signaling to functionally discrete cellular regions. Although N-Type VDCCs exist before birth which is consistent with a role in migration, most N-Type VDCCs subunit expression is postnatal and is important in the genesis of synaptic transmission in discrete hippocampal fields.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: BIII; Brain calcium channel III; calcium channel, L type, alpha-1 polypeptide; Calcium channel, L type, alpha-1 polypeptide isoform 5; calcium channel, voltage-dependent, L type, alpha 1B subunit; Voltage-dependent N-type calcium channel subunit alpha-1B; Voltage-gated calcium channel subunit alpha Cav2.2
Gene Aliases: alpha(1B); AW050276; AW060892; AW822256; Cach5; Cacna1b; Cacnl1a5; Cav2.2; Cchn1a
UniProt ID: (Mouse) O55017
Entrez Gene ID: (Mouse) 12287
nucleotide binding
ion channel activity
voltage-gated ion channel activity
voltage-gated calcium channel activity
calcium channel activity
calcium ion binding
protein binding
ATP binding
protein C-terminus binding
high voltage-gated calcium channel activity
metal ion binding
protein phosphatase 2A binding
positive regulation of neurotransmitter secretion
transport
ion transport
calcium ion transport
chemical synaptic transmission
neurotransmitter secretion
locomotory behavior
regulation of heart contraction
regulation of blood pressure
response to organic cyclic compound
sensory perception of pain
response to testosterone
regulation of ion transmembrane transport
response to pain
regulation of calcium ion transport
transmembrane transport
calcium ion import
calcium ion transmembrane transport
membrane depolarization during action potential
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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