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Invitrogen
CACNA2D2 Polyclonal Antibody
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FIGURE: 1 / 1
CACNA2D2 Antibody (PA5-68375) in IHC (P)
Immunohistochemical analysis of CACNA2D2 in paraffin-embedded Human esophagus cancer tissue using (left) CACNA2D2 Polyclonal Antibody (Product # PA5-68375) at a 1:45 dilution and (right) is treated with synthetic peptide. (Original magnification: x200).
Product Details
PA5-68375
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from human CACNA2D2.
Conjugate
Form
Liquid
Concentration
1.1 mg/mL
Purification
affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2688543
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha 2 delta calcium channel subunit; calcium channel, voltage dependent, alpha2/delta subunit 2; calcium channel, voltage-dependent, alpha 2/delta subunit 2; Cav alpha2/delta2; ducky; gene 26; Protein ducky; Voltage-dependent calcium channel subunit alpha-2/delta-2; Voltage-gated calcium channel subunit alpha-2/delta-2
Gene Aliases: a2d2; CACNA2D; CACNA2D2; du; KIAA0558; mKIAA0558; td; torpid
UniProt ID: (Human) Q9NY47, (Mouse) Q6PHS9, (Rat) Q8CFG6
Entrez Gene ID: (Human) 9254, (Mouse) 56808, (Rat) 300992
transport
ion transport
calcium ion transport
neuromuscular junction development
regulation of ion transmembrane transport
regulation of multicellular organism growth
positive regulation of organ growth
muscle fiber development
regulation of calcium ion transport
rhythmic synaptic transmission
calcium ion transmembrane transport
regulation of insulin secretion
cardiac conduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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