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Product Details
OSC00072W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from the c-terminal region of rat CACN conjugated to blue carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in mouse and shares 90% identity with human sequence.
Specificity of this antibody: CACNB3.
Target Information
CACNB3 encodes a regulatory beta subunit of the voltage-dependent calcium channel. Beta subunits are composed of five domains, which contribute to the regulation of surface expression and gating of calcium channels and may also play a role in the regulation of transcription factors and calcium transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CAB3; Calcium channel subunit beta 3; Calcium channel voltage-dependent subunit beta 3; calcium channel, voltage-dependent, beta 3 subunit; Cav; CCHB3; Voltage-dependent L-type calcium channel subunit beta-3
Gene Aliases: Beta3; Ca(v)beta3; CAB3; CACH3B; CACNB3; CACNLB3; Cchb3
UniProt ID: (Human) P54284, (Rat) P54287, (Mouse) P54285
Entrez Gene ID: (Human) 784, (Rat) 25297, (Mouse) 12297
calcium ion transport
chemical synaptic transmission
neuromuscular junction development
T cell receptor signaling pathway
calcium ion transmembrane transport
regulation of voltage-gated calcium channel activity
transport
membrane depolarization
calcium ion transport into cytosol
cardiac conduction
calcium ion transmembrane transport via high voltage-gated calcium channel
protein localization to plasma membrane
regulation of membrane repolarization during action potential
ion transport
regulation of ion transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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