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Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Bovine, Dog, Bat, Elephant, Panda, Horse, Rabbit, Pig, Opossum (100%).
This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily. The encoded protein has three Ig-like domains and a cytosolic protein 4.1 binding site near the C-terminus. Proteins belonging to the protein 4.1 family crosslink spectrin and interact with other cytoskeletal proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: Cell adhesion molecule 2; IgSF4D; Immunoglobulin superfamily member 4D; immunoglobulin superfamily, member 4D; NECL-3; nectin-like 3; Nectin-like protein 3; Synaptic cell adhesion molecule 2; SynCAM 2
Gene Aliases: CADM2; IGSF4D; Necl-3; NECL3; SynCAM 2; synCAM2
UniProt ID: (Human) Q8N3J6
Entrez Gene ID: (Dog) 487680, (Human) 253559, (Rabbit) 100340168
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