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Proteintech
CALCOCO1 Polyclonal Antibody
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Product Details
19843-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CALCOCO1 Fusion Protein Ag13876 (341-691 aa encoded by BC003177)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LKEQLRGAQ ELAASSQQKA TLLGEELASA AAARDRTIAE LHRSRLEVAE VNGRLAELGL HLKEEKCQWS KERAGLLQSV EAEKDKILKL SAEILRLEKA VQEERTQNQV FKTELAREKD SSLVQLSESK RELTELRSAL RVLQKEKEQL QEEKQELLEY MRKLEARLEK VADEKWNEDA TTEDEEAAVG LSCPAALTDS EDESPEDMRL PPYGLCERGD PGSSPAGPRE ASPLVVISQP APISPHLSGP AEDSSSDSEA EDEKSVLMAA VQSGGEEANL LLPELGSAFY DMASGFTVGT LSETSTGGPA TPTWKECPIC KERFPAESDK DALEDHMDGH FFFSTQDPFT FE (341-691 aa encoded by BC003177)
Target Information
CALCOCO1 (calcium-binding and coiled-coil domain-containing protein 1), also known as cocoa, calphoglin, sarcoma antigen NY-SAR-3 or coiled-coil coactivator protein, is a 691 amino acid protein that shuttles between the cytoplasm and nucleus and functions as coactivator for aryl hydrocarbon and nuclear receptors. A member of the CALCOCO family, CALCOCO1 is forms a calphoglin complex with PPA1 and PGM 1 and contains multiple functional domains through which it acts as a component of both the androgen signaling pathway and the Wnt/beta-catenin signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Calcium-binding and coiled-coil domain-containing protein 1; Calphoglin; Coiled-coil coactivator protein; coiled-coil leucine zipper coactivator 1; coiled-coil transcriptional coactivator; granule cell antiserum positive 11; GRIP1-interacting protein; inorganic pyrophosphatase activator; Sarcoma antigen NY-SAR-3
Gene Aliases: 1810009B06Rik; CALCOCO1; calphoglin; CocoA; Gcap11; KIAA1536; mKIAA1536; PP13275; UNQ2436/PRO4996
UniProt ID: (Human) Q9P1Z2, (Rat) Q66HR5, (Mouse) Q8CGU1
Entrez Gene ID: (Human) 57658, (Rat) 246047, (Mouse) 67488
core promoter binding
chromatin binding
transcription cofactor activity
transcription coactivator activity
protein binding
beta-catenin binding
protein C-terminus binding
ligand-dependent nuclear receptor transcription coactivator activity
sequence-specific DNA binding
transcription regulatory region DNA binding
armadillo repeat domain binding
molecular_function
biological_process
Wnt signaling pathway
transcription, DNA-templated
signal transduction
positive regulation of gene expression
intracellular steroid hormone receptor signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of nucleic acid-templated transcription
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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