Proteintech

CALN1 Polyclonal Antibody

CALN1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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CALN1 Antibody (11477-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human prostate cancer using 11477-1-AP (CALN1 antibody) at dilution of 1:100 (under 10x lens).

CALN1 Antibody in Immunoprecipitation (IP)

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Product Details

11477-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:1,000

View 5 publications 5 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CALN1 Fusion Protein Ag2043 (1-219 aa encoded by BC020200)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.53 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MPFHHVTAG LLYKGNYLNR SLSAGSDSEQ LANISVEELD EIREAFRVLD RDGNGFISKQ ELGMAMRSLG YMPSEVELAI IMQRLDMDGD GQVDFDEFMT ILGPKLVSSE GRDGFLGNTI DSIFWQFDMQ RITLEELKHI LYHAFRDHLT MKDIENIIIN EEESLNETSG NCQTEFEGVH SQKQNRQTCV RKSLICAFAM AFIISVMLIA ANQILRSGME (1-219 aa encoded by BC020200)

Target Information

Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP8, contains two EF-hand domains for calcium binding and shares 70% homology with CaBP7 and 50% homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. Both CaBP8 and CaBP7 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Identification of core genes in prefrontal cortex and hippocampus of Alzheimer's disease based on mRNA-miRNA network.

Journal of cellular and molecular medicine

Huang ZH,Wang H,Wang DM,Zhao XY,Liu WW,Zhong X,He DM,Mu BR,Lu MH

Thu Dec 01 00:00:00 UTC 2022

circEYA1 Functions as a Sponge of miR-582-3p to Suppress Cervical Adenocarcinoma Tumorigenesis via Upregulating CXCL14.

Molecular therapy. Nucleic acids

Xu J,Zhang Y,Huang Y,Dong X,Xiang Z,Zou J,Wu L,Lu W

Fri Dec 04 00:00:00 UTC 2020

Calneuron 1 Increased Ca²⁺ in the Endoplasmic Reticulum and Aldosterone Production in Aldosterone-Producing Adenoma.

Hypertension (Dallas, Tex. : 1979)

Kobuke K,Oki K,Gomez-Sanchez CE,Gomez-Sanchez EP,Ohno H,Itcho K,Yoshii Y,Yoneda M,Hattori N

Mon Jan 01 00:00:00 UTC 2018

Calneuron 1 Increased Ca²⁺ in the Endoplasmic Reticulum and Aldosterone Production in Aldosterone-Producing Adenoma.

Hypertension (Dallas, Tex. : 1979)

Kobuke K,Oki K,Gomez-Sanchez CE,Gomez-Sanchez EP,Ohno H,Itcho K,Yoshii Y,Yoneda M,Hattori N

Mon Jan 01 00:00:00 UTC 2018

Calneuron 1 Increased Ca²⁺ in the Endoplasmic Reticulum and Aldosterone Production in Aldosterone-Producing Adenoma.

Hypertension (Dallas, Tex. : 1979)

Kobuke K,Oki K,Gomez-Sanchez CE,Gomez-Sanchez EP,Ohno H,Itcho K,Yoshii Y,Yoneda M,Hattori N

Mon Jan 01 00:00:00 UTC 2018

Calneuron 1 Increased Ca²⁺ in the Endoplasmic Reticulum and Aldosterone Production in Aldosterone-Producing Adenoma.

Hypertension (Dallas, Tex. : 1979)

Kobuke K,Oki K,Gomez-Sanchez CE,Gomez-Sanchez EP,Ohno H,Itcho K,Yoshii Y,Yoneda M,Hattori N

Mon Jan 01 00:00:00 UTC 2018

Exosomal miR-675 from metastatic osteosarcoma promotes cell migration and invasion by targeting CALN1.

Biochemical and biophysical research communications

Gong L,Bao Q,Hu C,Wang J,Zhou Q,Wei L,Tong L,Zhang W,Shen Y

Sat Jun 02 00:00:00 UTC 2018

Exosomal miR-675 from metastatic osteosarcoma promotes cell migration and invasion by targeting CALN1.

Biochemical and biophysical research communications

Gong L,Bao Q,Hu C,Wang J,Zhou Q,Wei L,Tong L,Zhang W,Shen Y

Sat Jun 02 00:00:00 UTC 2018

Exosomal miR-675 from metastatic osteosarcoma promotes cell migration and invasion by targeting CALN1.

Biochemical and biophysical research communications

Gong L,Bao Q,Hu C,Wang J,Zhou Q,Wei L,Tong L,Zhang W,Shen Y

Sat Jun 02 00:00:00 UTC 2018

Exosomal miR-675 from metastatic osteosarcoma promotes cell migration and invasion by targeting CALN1.

Biochemical and biophysical research communications

Gong L,Bao Q,Hu C,Wang J,Zhou Q,Wei L,Tong L,Zhang W,Shen Y

Sat Jun 02 00:00:00 UTC 2018

Post-translational membrane insertion of tail-anchored transmembrane EF-hand Ca2+ sensor calneurons requires the TRC40/Asna1 protein chaperone.

The Journal of biological chemistry

Hradsky J,Raghuram V,Reddy PP,Navarro G,Hupe M,Casado V,McCormick PJ,Sharma Y,Kreutz MR,Mikhaylova M

Fri Oct 21 00:00:00 UTC 2011

Post-translational membrane insertion of tail-anchored transmembrane EF-hand Ca2+ sensor calneurons requires the TRC40/Asna1 protein chaperone.

The Journal of biological chemistry

Hradsky J,Raghuram V,Reddy PP,Navarro G,Hupe M,Casado V,McCormick PJ,Sharma Y,Kreutz MR,Mikhaylova M

Fri Oct 21 00:00:00 UTC 2011

Post-translational membrane insertion of tail-anchored transmembrane EF-hand Ca2+ sensor calneurons requires the TRC40/Asna1 protein chaperone.

The Journal of biological chemistry

Hradsky J,Raghuram V,Reddy PP,Navarro G,Hupe M,Casado V,McCormick PJ,Sharma Y,Kreutz MR,Mikhaylova M

Fri Oct 21 00:00:00 UTC 2011

Post-translational membrane insertion of tail-anchored transmembrane EF-hand Ca2+ sensor calneurons requires the TRC40/Asna1 protein chaperone.

The Journal of biological chemistry

Hradsky J,Raghuram V,Reddy PP,Navarro G,Hupe M,Casado V,McCormick PJ,Sharma Y,Kreutz MR,Mikhaylova M

Fri Oct 21 00:00:00 UTC 2011

Bioinformatics

Protein Aliases: CaBP8; Calcium-binding protein 8; calcium-binding protein CABP8; Calneuron I; Calneuron-1; calneuron-I

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Gene Aliases: 9630012C17Rik; CABP8; CALN1; MNCb-0849

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UniProt ID: (Human) Q9BXU9, (Mouse) Q9JJG7, (Rat) Q06BI3

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Entrez Gene ID: (Human) 83698, (Mouse) 140904, (Rat) 363909

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Function(s)

calcium ion binding metal ion binding

Process(es)

biological_process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CALN1 Polyclonal Antibody

CALN1 Antibody (11477-1-AP) in IHC (P)

Product Details

11477-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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