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Invitrogen
CAP1 Polyclonal Antibody
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FIGURE: 1 / 4
CAP1 Antibody (PA5-114940) in ICC/IF
Immunocytochemistry analysis of CAP1 in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-114940) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated goat anti-mouse IgG (Green) and DAPI (blue) using a dilution of 1:200 (1 hr at 37°C).
Product Details
PA5-114940
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CAP1(Accession Q01518), corresponding to amino acid residues S275-E325.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2899576
Product Specific Information
Antibody detects endogenous levels of total CAP1.
Target Information
Adenylyl cyclase-associated protein 1 is an enzyme that in humans is encoded by the CAP1 gene. This gene is mapped to 1p34. 2. The protein encoded by this gene is related to the S. cerevisiae CAP protein, which is involved in the cyclic AMP pathway. And the human protein is able to interact with other molecules of the same protein, as well as with CAP2 and actin. Alternatively spliced transcript variants have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adenylyl cyclase-associated CAP protein, yeast homolog 1; Adenylyl cyclase-associated protein 1; CAP 1; CAP, adenylate cyclase-associated protein 1; cyclase-associated protein homologue; RP11-115D7.1; testis secretory sperm-binding protein Li 218p
Gene Aliases: CAP; CAP1; CAP1-PEN; Mch1
UniProt ID: (Human) Q01518, (Rat) Q08163, (Mouse) P40124
Entrez Gene ID: (Human) 10487, (Rat) 64185, (Mouse) 12331
cell morphogenesis
ameboidal-type cell migration
receptor-mediated endocytosis
biological_process
actin cytoskeleton organization
establishment or maintenance of cell polarity
signal transduction
activation of adenylate cyclase activity
actin polymerization or depolymerization
cytoskeleton organization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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