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Product Details
H00011131-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CAPN11 (AAH33733.1, 1 a.a. approximately 702 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MVAHINNSRL KAKGVGQHDN AQNFGNQSFE ELRAACLRKG ELFEDPLFPA EPSSLGFKDL GPNSKNVQNI SWQRPKDIIN NPLFIMDGIS PTDICQGILG DCWLLAAIGS LTTCPKLLYR VVPRGQSFKK NYAGIFHFQI WQFGQWVNVV VDDRLPTKND KLVFVHSTER SEFWSALLEK AYAKLSGSYE ALSGGSTMEG LEDFTGGVAQ SFQLQRPPQN LLRLLRKAVE RSSLMGCSIE VTSDSELESM TDKMLVRGHA YSVTGLQDVH YRGKMETLIR VRNPWGRIEW NGAWSDSARE WEEVASDIQM QLLHKTEDGE FWMSYQDFLN NFTLLEICNL TPDTLSGDYK SYWHTTFYEG SWRRGSSAGG CRNHPGTFWT NPQFKISLPE GDDPEDDAEG NVVACTCLVA LMQKNWRHAR QQGAQLQTIG FVLYAVPKEF QNIQDVHLKK EFFTKYQDHG FSEIFTNSRE VSSQLRLPPG EYIIIPSTFE PHRDADFLLR VFTEKHSESW ELDEVNYAEQ LQEEKVSEDD MDQDFLHLFK IVAGEGKEIG VYELQRLLNR MAIKFKSFKT KGFGLDACRC MINLMDKDGS GKLGLLEFKI LWKKLKKWMD IFRECDQDHS GTLNSYEMRL VIEKAGIKLN NKVMQVLVAR YADDDLIIDF DSFISCFLRL KTMFTFFLTM DPKNTGHICL SLEQWLQMTM WG
Target Information
The calpains including Calpain 1 (CAPN1), calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Calcium-activated neutral proteinase 11; Calpain-11; CANP 11; HIP2; LIG
Gene Aliases: calpain11; CAPN11
UniProt ID: (Human) Q9UMQ6
Entrez Gene ID: (Human) 11131
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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