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Invitrogen
CAPZB Polyclonal Antibody
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Product Details
PA5-96935
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-272 of human CAPZB (NP_0049211)
Conjugate
Form
Liquid
Concentration
1.1 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2808737
Product Specific Information
Immunogen sequence: MSDQQLDCAL DLMRRLPPQQ IEKNLSDLID LVPSLCEDLL SSVDQPLKIA RDKVVGKDYL LCDYNRDGDS YRSPWSNKYD PPLEDGAMPS ARLRKLEVEA NNAFDQYRDL YFEGGVSSVY LWDLDHGFAG VILIKKAGDG SKKIKGCWDS IHVVEVQEKS SGRTAHYKLT STVMLWLQTN KSGSGTMNLG GSLTRQMEKD ETVSDCSPHI ANIGRLVEDM ENKIRSTLNE IYFGKTKDIV NGLRSVQTFA DKSKQEALKN DLVEALKRKQ QC; Positive Samples: A-431, THP-1, HeLa, Mouse brain, Mouse testis, Mouse spleen, Rat small intestine; Cellular Location: Cytoplasm, cytoskeleton, myofibril, sarcomere
Target Information
CAPZB is a member of the F-actin capping protein family. This gene encodes the beta subunit of the barbed-end actin binding protein. The protein regulates growth of the actin filament by capping the barbed end of growing actin filaments.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cap Z; capping protein (actin filament) muscle Z-line, beta; capping protein beta 1; CapZ beta; F-actin capping protein beta subunit; F-actin-capping protein subunit beta; MGC104401; MGC129749; MGC129750; RP4-657E11.7
Gene Aliases: 1700120C01Rik; AI325129; CAPB; CAPPB; Cappb1; CAPZ; CAPZB; CPB1; CPB2; CPbeat2; CPbeta1; CPbeta2
UniProt ID: (Human) P47756, (Rat) Q5XI32, (Mouse) P47757
Entrez Gene ID: (Human) 832, (Rat) 298584, (Mouse) 12345
cell morphogenesis
cytoskeleton organization
biological_process
regulation of lamellipodium assembly
regulation of cell morphogenesis
cell projection organization
lamellipodium assembly
actin cytoskeleton organization
negative regulation of microtubule polymerization
neuron projection development
muscle fiber development
barbed-end actin filament capping
negative regulation of filopodium assembly
regulation of protein kinase C signaling
movement of cell or subcellular component
blood coagulation
cell-cell adhesion
actin filament capping
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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