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Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. [UniProt]
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Protein Aliases: ATP-dependent (S)-NAD(P)H-hydrate dehydratase; ATP-dependent (S)-NAD(P)H-hydrate dehydratase {ECO:0000255|HAMAP-Rule:MF_03157}; ATP-dependent NAD(P)H-hydrate dehydratase; ATP-dependent NAD(P)HX dehydratase; ATP-dependent NAD(P)HX dehydratase {ECO:0000255|HAMAP-Rule:MF_03157}; carbohydrate kinase domain containing; Carbohydrate kinase domain-containing protein; carbohydrate kinase domain-containing protein {ECO:0000255|HAMAP-Rule:MF_03157}; NAD(P)HX dehydratase
Gene Aliases: 0710008K08Rik; 2810407E01Rik; CARKD; LP3298; NAXD; RGD1562691
UniProt ID: (Mouse) Q9CZ42, (Human) Q8IW45
Entrez Gene ID: (Mouse) 69225, (Rat) 361185, (Human) 55739
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