Proteintech

CBP20 Polyclonal Antibody

CBP20 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 2

CBP20 Antibody (11950-1-AP) in ICC/IF

Immunofluorescent analysis of ( 4% PFA) fixed HeLa cells using 11950-1-AP (CBP20 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

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Product Details

11950-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 2 publications 2 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:50-1:500

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CBP20 Fusion Protein Ag2550 (1-156 aa encoded by BC001255)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.17 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MSGGLLKAL RSDSYVELSQ YRDQHFRGDN EEQEKLLKKS CTLYVGNLSF YTTEEQIYEL FSKSGDIKKI IMGLDKMKKT ACGFCFVEYY SRADAENAMR YINGTRLDDR IIRTDWDAGF KEGRQYGRGR SGGQVRDEYR QDYDAGRGGY GKLAQNQ (1-156 aa encoded by BC001255)

Target Information

The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

N7-methylguanosin regulators-mediated methylation modification patterns and characterization of the immune microenvironment in lower-grade glioma.

European journal of medical research

Maimaiti A,Feng Z,Liu Y,Turhon M,Xie Z,Baihetiyaer Y,Wang X,Kasimu M,Jiang L,Wang Y,Wang Z,Pei Y

Thu Mar 30 00:00:00 UTC 2023

N7-methylguanosin regulators-mediated methylation modification patterns and characterization of the immune microenvironment in lower-grade glioma.

European journal of medical research

Maimaiti A,Feng Z,Liu Y,Turhon M,Xie Z,Baihetiyaer Y,Wang X,Kasimu M,Jiang L,Wang Y,Wang Z,Pei Y

Thu Mar 30 00:00:00 UTC 2023

Multi-omics approach reveals posttranscriptionally regulated genes are essential for human pluripotent stem cells.

iScience

Iwasaki M,Kawahara Y,Okubo C,Yamakawa T,Nakamura M,Tabata T,Nishi Y,Narita M,Ohta A,Saito H,Yamamoto T,Nakagawa M,Yamanaka S,Takahashi K

Fri May 20 00:00:00 UTC 2022

Bioinformatics

Protein Aliases: 20 kDa nuclear cap-binding protein; CBP20; Cell proliferation-inducing gene 55 protein; NCBP 20 kDa subunit; NCBP interacting protein 1; NCBP-interacting protein 1; NIP1; nuclear cap binding protein subunit 2, 20kD; nuclear cap binding protein subunit 2, 20kDa; Nuclear cap-binding protein subunit 2

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Gene Aliases: 20kDa; 5930413E18Rik; AA536802; AI843301; C79367; CBC2; CBP20; NCBP2; NIP1; PIG55

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UniProt ID: (Human) P52298, (Mouse) Q9CQ49, (Rat) B1WC40

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Entrez Gene ID: (Human) 22916, (Mouse) 68092, (Rat) 689116

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Function(s)

nucleotide binding RNA cap binding RNA 7-methylguanosine cap binding RNA binding mRNA binding protein binding snRNA binding poly(A) RNA binding nucleic acid binding

Process(es)

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay mRNA splicing, via spliceosome 7-methylguanosine mRNA capping mRNA processing regulation of translation regulation of translational initiation transport RNA splicing gene silencing by RNA mRNA cis splicing, via spliceosome mRNA transport transcription from RNA polymerase II promoter transcription elongation from RNA polymerase II promoter termination of RNA polymerase II transcription RNA export from nucleus mRNA export from nucleus snRNA export from nucleus histone mRNA metabolic process fibroblast growth factor receptor signaling pathway gene expression mRNA 3'-end processing positive regulation of mRNA 3'-end processing snRNA transcription from RNA polymerase II promoter positive regulation of RNA export from nucleus nuclear export pre-mRNA cleavage required for polyadenylation regulation of mRNA polyadenylation biological_process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CBP20 Polyclonal Antibody

CBP20 Antibody (11950-1-AP) in ICC/IF

Product Details

11950-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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