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Invitrogen
CBR3 Polyclonal Antibody
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CBR3 Antibody (PA5-121115) in WB
Western blot analysis of CBR3 in extracts of various cell lines. Samples were incubated with CBR3 Polyclonal antibody (Product # PA5-121115) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-121115
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 118-277 of human CBR3 (NP_001227.1).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914687
Product Specific Information
Positive test controls include: SW480, NCI-H460, MCF7, BT-474, Mouse lung, Mouse brain, Mouse ovary, Rat brain. The target is usually found in the following locations: Cytoplasm.
Immunogen sequence: TRNMCNELLP IMKPHGRVVN ISSLQCLRAF ENCSEDLQER FHSETLTEGD LVDLMKKFVE DTKNEVHERE GWPNSPYGVS KLGVTVLSRI LARRLDEKRK ADRILVNACC PGPVKTDMDG KDSIRTVEEG AETPVYLALL PPDATEPQGQ LVHDKVVQNW
Target Information
Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: carbonyl reductase (NADPH) 3; Carbonyl reductase [NADPH] 3; epididymis secretory protein Li 25; Monomeric carbonyl reductase 3; NADPH-dependent carbonyl reductase 3; Quinone reductase CBR3; Short chain dehydrogenase/reductase family 21C member 2; short chain dehydrogenase/reductase family 21C, member 2
Gene Aliases: 1110001J05Rik; C81353; CBR3; hCBR3; HEL-S-25; SDR21C2
UniProt ID: (Human) O75828, (Mouse) Q8K354, (Rat) B2GV72
Entrez Gene ID: (Human) 874, (Mouse) 109857, (Rat) 304078
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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