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Invitrogen
CBR4 Polyclonal Antibody
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Product Details
PA5-57977
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CBR4. Recombinant protein control fragment (Product #RP-96684).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2639330
Product Specific Information
Immunogen sequence: FLVNAAGINR DGLLVRTKTE DMVSQLHTNL LGSMLTCKAA MRTMIQQQGG SIVNVGSIVG LKGNSGQSVY SAS
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 86%.
Target Information
The heterotetramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis. Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD. The homotetramer has NADPH-dependent quinone reductase activity. Both homotetramer and the heterotetramer have broad substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3-ketoacyl-[acyl-carrier-protein] reductase beta subunit; 3-oxoacyl-[acyl-carrier-protein] reductase; carbonic reductase 4; Carbonyl reductase family member 4; CBR4; KAR beta subunit; Quinone reductase CBR4; Short chain dehydrogenase/reductase family 45C member 1; short chain dehydrogenase/reductase family 45C, member 1
Gene Aliases: CBR4; SDR45C1
UniProt ID: (Human) Q8N4T8
Entrez Gene ID: (Human) 84869
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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