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Invitrogen
CBWD2 Polyclonal Antibody
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Product Details
PA5-40114
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human CBWD2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.97 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% Thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2606875
Product Specific Information
Recommended positive controls: THP-1 cells.
Predicted reactivity: Human (99%), Dog (88%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The CBWD2 gene, a member of the CobW domain-containing (CBWD) gene family, encodes a protein involved in vitamin B12 synthesis. This gene is part of a conserved pathway crucial for cobalamin biosynthesis, typically in microorganisms. In dinoflagellates, the CBWD gene family, including CBWD2, has been identified to play a role in the synthesis and regulation of vitamin B12, essential for various metabolic processes. The CobW domain is implicated in interactions with cobalt, a vital component of the vitamin B12 molecule, suggesting a regulatory or structural role in cobalamin assembly. Research on the CBWD2 gene and its protein products can provide insights into the complex mechanisms of vitamin B12 biosynthesis and its evolutionary significance in eukaryotic organisms, possibly opening avenues for biotechnological applications in vitamin B12 production.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cobalamin synthase W domain-containing protein 2; cobalamin synthetase W domain-containing protein 2; COBW domain-containing protein 2; Zinc-regulated GTPase metalloprotein activator 1B
Gene Aliases: CBWD2; ZNG1B
UniProt ID: (Human) Q8IUF1
Entrez Gene ID: (Human) 150472
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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