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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • CBX7 Antibodies

          Invitrogen

          CBX7 Polyclonal Antibody

          1 Published Figure
          1 Reference
          View all (13) CBX7 antibodies

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          Datasheet
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          Cite CBX7 Polyclonal Antibody

          • Antibody Testing Data (2)
          • Published Figures (1)
          CBX7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          CBX7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          CBX7 Antibody (PA5-61801) in IHC (P)

          Immunohistochemical analysis of CBX7 in human kidney using CBX7 Polyclonal Antibody (Product # PA5-61801) shows strong cytoplasmic and nuclear positivity in cells in tubules. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CBX7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CBX7 Antibody in Western Blot (WB)
          CBX7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

          Product Details

          PA5-61801

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:50
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human CBX7. Recombinant protein control fragment (Product #RP-103031).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2639334

          Product Specific Information

          Immunogen sequence: ADADLAEGPP PWTPALPSSE VTVTDITANS ITVTFREAQA AEGFFRDRSG KF

          Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 88%.

          Target Information

          The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: chromobox homolog 7; Chromobox protein homolog 7

          View more View less

          Gene Aliases: CBX7

          View more View less

          UniProt ID: (Human) O95931

          View more View less

          Entrez Gene ID: (Human) 23492

          View more View less

          Function(s)
          chromatin binding single-stranded RNA binding protein binding methylated histone binding
          Process(es)
          negative regulation of transcription from RNA polymerase II promoter transcription, DNA-templated covalent chromatin modification response to drug sebaceous gland development
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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