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Proteintech
CC2D1A Polyclonal Antibody
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Product Details
16816-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CC2D1A Fusion Protein Ag10355 (1-351 aa encoded by BC064981)
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MHKRKGPPG PPGRGAAAAR QLGLLVDLSP DGLMIPEDGA NDEELEAEFL ALVGGQPPAL EKLKGKGPLP MEAIEKMASL CMRDPDEDEE EGTDEDDLEA DDDLLAELNE VLGEEQKASE TPPPVAQPKP EAPHPGLETT LQERLALYQT AIESARQAGD SAKMRRYDRG LKTLENLLAS IRKGNAIDEA DIPPPVAIGK GPASTPTYSP APTQPAPRIA SAPEPRVTLE GPSATAPASS PGLAKPQMPP GPCSPGPLAQ LQSRQRDYKL AALHAKQQGD TTAAARHFRV AKSFDAVLEA LSRGEPVDLS CLPPPPDQLP PDPPSPPSQP PTPATAPSTT EVPPPPRTLL EA (1-351 aa encoded by BC064981)
Target Information
This gene encodes a transcriptional repressor that binds to a conserved 14-bp 5'-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A mutation in this gene results in nonsyndromic mental retardation-3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 5-HT1A receptor; Akt kinase-interacting protein 1; Coiled-coil and C2 domain-containing protein 1A; Five prime repressor element under dual repression-binding protein 1; five repressor element under dual repression-binding protein 1; five' repressor element under dual repression binding protein 1; FLJ20241; FRE under dual repression-binding protein 1; freud-1; mental retardation, nonsyndromic, autosomal recessive, 3; Putative NF-kappa-B-activating protein 023N; putative NFkB activating protein
Gene Aliases: AKI1; BC016188; CC2D1A; FREUD-1; Freud-1/Aki1; LGD2; MRT3; RGD1306108; Tape
UniProt ID: (Human) Q6P1N0, (Rat) Q66HA5, (Mouse) Q8K1A6
Entrez Gene ID: (Human) 54862, (Rat) 288908, (Mouse) 212139
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
signal transducer activity
protein binding
cadherin binding involved in cell-cell adhesion
DNA binding
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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