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CCAR2 Polyclonal Antibody

CCAR2 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 14

CCAR2 Antibody (22638-1-AP) in ICC/IF

Immunofluorescent analysis of HepG2 cells, using KIAA1967 antibody 22638-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IGG (red).

CCAR2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

CCAR2 Antibody in Immunoprecipitation (IP)

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Product Details

22638-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 2 publications 2 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:20-1:200

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

View 2 publications 2 publications

RNA Immunoprecipitation (RIP)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CCAR2 Fusion Protein Ag18374 (571-923 aa encoded by BC018269)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.44 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: EPEKEEAAK EEATKEEEAI KEEVVKEPKD EAQNEGPATE SEAPLKEDGL LPKPLSSGGE EEEKPRGEAS EDLCEMALDP ELLLLRDDGE EEFAGAKLED SEVRSVASNQ SEMEFSSLQD MPKELDPSAV LPLDCLLAFV FFDANWCGYL HRRDLERILL TLGIRLSAEQ AKQLVSRVVT QNICQYRSLQ YSRQEGLDGG LPEEVLFGNL DLLPPPGKST KPGAAPTEHK ALVSHNGSLI NVGSLLQRAE QQDSGRLYLE NKIHTLELKL EESHNRFSAT EVTNKTLAAE MQELRVRLAE AEETARTAER QKSQLQRLLQ ELRRRLTPLQ LEIQRVVEKA DSWVEKEEPA PSN (571-923 aa encoded by BC018269)

Target Information

DBC1 is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers. It contains a 5' CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder cancers.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Hypoxia-induced proteasomal degradation of DBC1 by SIAH2 in breast cancer progression.

eLife

Liu Q,Luo Q,Feng J,Zhao Y,Ma B,Cheng H,Zhao T,Lei H,Mu C,Chen L,Meng Y,Zhang J,Long Y,Su J,Chen G,Li Y,Hu G,Liao X,Chen Q,Zhu Y

Mon Aug 01 00:00:00 UTC 2022

Hypoxia-induced proteasomal degradation of DBC1 by SIAH2 in breast cancer progression.

eLife

Liu Q,Luo Q,Feng J,Zhao Y,Ma B,Cheng H,Zhao T,Lei H,Mu C,Chen L,Meng Y,Zhang J,Long Y,Su J,Chen G,Li Y,Hu G,Liao X,Chen Q,Zhu Y

Mon Aug 01 00:00:00 UTC 2022

Hypoxia-induced proteasomal degradation of DBC1 by SIAH2 in breast cancer progression.

eLife

Liu Q,Luo Q,Feng J,Zhao Y,Ma B,Cheng H,Zhao T,Lei H,Mu C,Chen L,Meng Y,Zhang J,Long Y,Su J,Chen G,Li Y,Hu G,Liao X,Chen Q,Zhu Y

Mon Aug 01 00:00:00 UTC 2022

Corrigendum to article "Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation''.

Nucleic acids research

Chen R,Liu Y,Zhuang H,Yang B,Hei K,Xiao M,Hou C,Gao H,Zhang X,Jia C,Li L,Li Y,Zhang N

Mon Apr 19 00:00:00 UTC 2021

Corrigendum to article "Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation''.

Nucleic acids research

Chen R,Liu Y,Zhuang H,Yang B,Hei K,Xiao M,Hou C,Gao H,Zhang X,Jia C,Li L,Li Y,Zhang N

Mon Apr 19 00:00:00 UTC 2021

Chromatin remodeling factor CECR2 forms tissue-specific complexes with CCAR2 and LUZP1.

Biochemistry and cell biology = Biochimie et biologie cellulaire

Niri F,Terpstra AN,Lim KRQ,McDermid HE

Wed Dec 01 00:00:00 UTC 2021

Chromatin remodeling factor CECR2 forms tissue-specific complexes with CCAR2 and LUZP1.

Biochemistry and cell biology = Biochimie et biologie cellulaire

Niri F,Terpstra AN,Lim KRQ,McDermid HE

Wed Dec 01 00:00:00 UTC 2021

Bioinformatics

Protein Aliases: Cell cycle and apoptosis regulator protein 2; Cell division cycle and apoptosis regulator protein 2; DBC-1; DBC.1; DBCCR1; DBIRD complex subunit KIAA1967; deleted in breast cancer 1; Deleted in breast cancer gene 1 protein; FAM5A; NET35; p30 DBC; p30 DBC protein

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Gene Aliases: 2610301G19Rik; CCAR2; DBC-1; DBC1; KIAA1967; mKIAA1967; NET35; p30 DBC; p30DBC; RGD1309922

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UniProt ID: (Human) Q8N163, (Mouse) Q8VDP4

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Entrez Gene ID: (Human) 57805, (Mouse) 219158, (Rat) 306007

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Function(s)

RNA polymerase II core binding enzyme inhibitor activity protein binding enzyme binding poly(A) RNA binding

Process(es)

transcription, DNA-templated mRNA processing cellular response to DNA damage stimulus cell cycle RNA splicing response to UV Wnt signaling pathway negative regulation of cell growth regulation of protein stability negative regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of DNA-templated transcription, elongation regulation of circadian rhythm positive regulation of apoptotic process negative regulation of catalytic activity mitochondrial fragmentation involved in apoptotic process negative regulation of transcription, DNA-templated rhythmic process positive regulation of canonical Wnt signaling pathway regulation of protein deacetylation regulation of cellular response to heat negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage positive regulation of DNA damage checkpoint regulation of transcription, DNA-templated apoptotic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CCAR2 Polyclonal Antibody

CCAR2 Antibody (22638-1-AP) in ICC/IF

Product Details

22638-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

RNA Immunoprecipitation (RIP)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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