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Proteintech
CCDC109B Polyclonal Antibody
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Product Details
20387-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CCDC109B Fusion Protein Ag14225 (1-230 aa encoded by BC002633)
Conjugate
Form
Liquid
Concentration
0.28 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MLQRGLWPW RTRLLPTPGT WRPARPWPLP PPPQVLRVKL CGNVKYYQSH HYSTVVPPDE ITVIYRHGLP LVTLTLPSRK ERCQFVVKPM LSTVGSFLQD LQNEDKGIKT AAIFTADGNM ISASTLMDIL LMNDFKLVIN KIAYDVQCPK REKPSNEHTA EMEHMKSLVH RLFTILHLEE SQKKREHHLL EKIDHLKEQL QPLEQVKAGI EAHSEAKTSG LLWAGLALLS I (1-230 aa encoded by BC002633)
Target Information
Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Calcium uniporter regulatory subunit MCUb, mitochondrial; coiled-coil domain containing 109B; Coiled-coil domain-containing protein 109B; MCUb; mitochondrial calcium uniporter regulatory subunit MCUb
Gene Aliases: CCDC109B; MCUB
UniProt ID: (Human) Q9NWR8
Entrez Gene ID: (Human) 55013
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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