Proteintech

CCDC41 Polyclonal Antibody

CCDC41 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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CCDC41 Antibody (26013-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using (Product # 26013-1-AP) (CCDC41 antibody) at dilution of 1:200 (under 10x lens).

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Product Details

26013-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200

Immunocytochemistry (ICC/IF)

View 4 publications 4 publications

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CCDC41 Fusion Protein Ag22826 (351-693 aa encoded by BC125087)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.33 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MQATVRSLE AEKQSANLRA ERLEKELQSS SEQNTFLINK LHKAEREINT LSSKVKELKH SNKLEITDIK LETARAKSEL ERERNKIQSE LDGLQSDNEI LKAAVEHHKV LLVEKDRELI RKVQAAKEEG YQKLVVLQDE KLELENRLAD LEKMKVEHDV WRQSEKDQYE EKLRASQMAE EITRKELQSV RLKLQQQIVT IENAEKEKNE NSDLKQQISS LQIQVTSLAQ SENDLLNSNQ MLKEMVERLK QECRNFRSQA EKAQLEAEKT LEEKQIQWLE EKHKLHERIT DREEKYNQAK EKLQRAAIAQ KKLEQDLELG CPSVTDTYRE SVFPPPPLKR DLLK (351-693 aa encoded by B C125087)

Target Information

Component of the distal appendage region of the centriole involved in the initiation of primary cilium assembly. May collaborate with IFT20 in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium during the initiation of primary cilium assembly.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

A hierarchical pathway for assembly of the distal appendages that organize primary cilia.

bioRxiv : the preprint server for biology

Kanie T,Love JF,Fisher SD,Gustavsson AK,Jackson PK

Tue Jan 10 00:00:00 UTC 2023

A stress-induced cilium-to-PML-NB route drives senescence initiation.

Nature communications

Ma X,Zhang Y,Zhang Y,Zhang X,Huang Y,He K,Chen C,Hao J,Zhao D,LeBrasseur NK,Kirkland JL,Chini EN,Wei Q,Ling K,Hu J

Mon Apr 03 00:00:00 UTC 2023

A stress-induced cilium-to-PML-NB route drives senescence initiation.

Nature communications

Ma X,Zhang Y,Zhang Y,Zhang X,Huang Y,He K,Chen C,Hao J,Zhao D,LeBrasseur NK,Kirkland JL,Chini EN,Wei Q,Ling K,Hu J

Mon Apr 03 00:00:00 UTC 2023

The evolutionary conserved proteins CEP90, FOPNL, and OFD1 recruit centriolar distal appendage proteins to initiate their assembly.

PLoS biology

Le Borgne P,Greibill L,Laporte MH,Lemullois M,Bouhouche K,Temagoult M,Rosnet O,Le Guennec M,Lignières L,Chevreux G,Koll F,Hamel V,Guichard P,Tassin AM

Thu Sep 01 00:00:00 UTC 2022

NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis.

Cell research

Liu M,Zhang W,Li M,Feng J,Kuang W,Chen X,Yang F,Sun Q,Xu Z,Hua J,Yang C,Liu W,Shu Q,Yang Y,Zhou T,Xie S

Mon Nov 01 00:00:00 UTC 2021

NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis.

Cell research

Liu M,Zhang W,Li M,Feng J,Kuang W,Chen X,Yang F,Sun Q,Xu Z,Hua J,Yang C,Liu W,Shu Q,Yang Y,Zhou T,Xie S

Mon Nov 01 00:00:00 UTC 2021

Requirement of NPHP5 in the hierarchical assembly of basal feet associated with basal bodies of primary cilia.

Cellular and molecular life sciences : CMLS

Hossain D,Barbelanne M,Tsang WY

Wed Jan 01 00:00:00 UTC 2020

The C7orf43/TRAPPC14 component links the TRAPPII complex to Rabin8 for preciliary vesicle tethering at the mother centriole during ciliogenesis.

The Journal of biological chemistry

Cuenca A,Insinna C,Zhao H,John P,Weiss MA,Lu Q,Walia V,Specht S,Manivannan S,Stauffer J,Peden AA,Westlake CJ

Fri Oct 18 00:00:00 UTC 2019

Bioinformatics

Protein Aliases: centrosomal protein 83kDa; Centrosomal protein of 83 kDa; Cep83; coiled-coil domain containing 41; Coiled-coil domain-containing protein 41; NY-REN-58 antigen; Renal carcinoma antigen NY-REN-58

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Gene Aliases: CCDC41; CEP83; NPHP18; NY-REN-58

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UniProt ID: (Human) Q9Y592

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Entrez Gene ID: (Human) 51134

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Function(s)

molecular_function protein binding

Process(es)

cilium assembly vesicle docking protein localization to centrosome

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CCDC41 Polyclonal Antibody

CCDC41 Antibody (26013-1-AP) in IHC (P)

Product Details

26013-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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