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Proteintech
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Immunogen sequence: MAMEAGLSE VKSELQSRDD LLRIIEMERL QLHRELLKIG ECQNAQGNKT RLESSYLPSI KEPERKIKEL FSVMQDQPNH EKELNKIRSQ LQQVEEYHNS EQERMRNEIS DLTEELHQKE ITIATVTKKA ALLEKQLKME LEIKEKMLAK QKVSDMKYKA VRTENTHLKG MMGDLDPGEY MSMDFTNREQ SRHTSINKLQ YENERLRNDL AKLHVNGKST WTNQNTYEET GRYAYQSQIK VEQNEERLSH DCEPNRSTMP PLPPSTFQAK EMTSPLVSDD DVFPLSPPDM SFPASLAAQH FLLEEEKRAK ELEKLLNTHI DELQRHTEFT LNKYSKLKQN RHI (264-604 aa encoded by BC031247)
CCDC67 (deuterosome assembly protein 1) is a key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. The protein interacts with CEP152 and recruits PLK4 to activate centriole biogenesis
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: coiled-coil domain containing 67; Coiled-coil domain-containing protein 67; deuterosomal protein 1; Deuterosome assembly protein 1; deuterosome protein 1
Gene Aliases: 4933401K09Rik; CCDC67; DEUP1
UniProt ID: (Mouse) Q7M6Y5, (Human) Q05D60
Entrez Gene ID: (Mouse) 234964, (Human) 159989
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