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Invitrogen
CCDC90B Polyclonal Antibody
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Product Details
PA5-31579
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human CCDC90B. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2549052
Product Specific Information
Recommended positive controls: MCF-7, mouse heart.
Predicted reactivity: Mouse (91%), Rat (88%), Rhesus Monkey (97%), Chimpanzee (99%), Bovine (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CCDC90B (Coiled-Coil Domain-Containing 90B), also known as MCUR1 (Mitochondrial Calcium Uniporter Regulator 1), is a gene located on chromosome 16p13.3 that encodes a protein involved in mitochondrial function. MCUR1 is a critical component of the mitochondrial calcium uniporter complex, which plays a vital role in regulating mitochondrial calcium uptake. Calcium uptake by mitochondria is essential for cellular metabolism, energy production, and apoptosis. MCUR1 interacts with other components of the uniporter complex to modulate the entry of calcium into the mitochondrial matrix, thereby influencing mitochondrial bioenergetics and reactive oxygen species (ROS) generation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Coiled-coil domain-containing protein 90B, mitochondrial
Gene Aliases: 2310015N07Rik; C86558; CCDC90B; CUA003; MDS011; MDS025
UniProt ID: (Human) Q9GZT6, (Mouse) Q8C3X2
Entrez Gene ID: (Human) 60492, (Mouse) 66365
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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