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Invitrogen
CCDC91 Polyclonal Antibody
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Product Details
PA5-78525
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human CCDC91. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2735599
Product Specific Information
Positive Control: 293T, A431, HeLa, HepG2
Predicted Reactivity: Pig (94%), Bovine (93%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CCDC91 (Coiled-Coil Domain-Containing 91) is a gene located on chromosome 12q24.31 that encodes a protein involved in vesicle-mediated transport and Golgi function. The CCDC91 protein contains coiled-coil domains, which facilitate protein-protein interactions necessary for its role in the secretory pathway. Specifically, CCDC91 is a component of the Golgi-associated retrograde protein (GARP) complex, which is essential for the recycling of transport vesicles from endosomes to the trans-Golgi network (TGN). Research has revealed that CCDC91 is crucial for maintaining Golgi structure and function and is involved in the sorting and trafficking of proteins and lipids within the cell. The protein's interactions with other components of the vesicular transport machinery enable the efficient movement of cargo between organelles, which is critical for various cellular processes, including secretion, endocytosis, and lysosomal degradation. Mutations or dysregulation of CCDC91 can disrupt these processes, potentially leading to diseases associated with vesicle trafficking defects, such as certain neurodegenerative disorders and cancer.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Coiled-coil domain-containing protein 91; GGA binding partner; GGA-binding partner; p56 accessory protein
Gene Aliases: CCDC91; GGABP; HSD8; p56
UniProt ID: (Human) Q7Z6B0
Entrez Gene ID: (Human) 55297
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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