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Proteintech
CCDC99 Polyclonal Antibody
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Product Details
24689-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CCDC99 Fusion Protein Ag20430 (259-605 aa encoded by BC012568)
Conjugate
Form
Liquid
Concentration
0.28 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: AEVEDRRAA MERQLISMKV KYQSLKKQNV FNREQMQRMK LQIATLLQMK GSQTEFEQQE RLLAMLEQKN GEIKHLLGEI RNLEKFKNLY DSMESKPSVD SGTLEDNTYY TDLLQMKLDN LNKEIESTKG ELSIQRMKAL FESQRALDIE RKLFANERCL QLSESENMKL RAKLDELKLK YEPEETVEVP VLKKRREVLP VDITTAKDAC VNNSALGGEV YRLPPQKEET QSCPNSLEDN NLQLEKSVSI HTPVVSLSPH KNLPVDMQLK KEKKCVKLIG VPADAEALSE RSGNTPNSPR LAAESKLQTE VKEGKETSSK LEKETCKKSH PILYVSSKST PETQCPQQ (259-605 aa encoded by BC012568)
Target Information
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridizations indicate that this lectin is specifically expressed in keratinocytes. It is expressed at all stages of epidermal differentiation (i.e., in basal and suprabasal layers). The protein was found mainly in stratified squamous epithelium. It is moderately repressed by retinoic acid. The antigen localized to basal keratinocytes, although it was also found at lower levels in the suprabasal layers, where it concentrated to areas of cell-to-cell contact. The cellular localization and its striking down-regulation in cultured keratinocytes imply a role in cell-cell and/or cell-matrix interactions necessary for normal growth control.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Arsenite-related gene 1 protein; coiled-coil domain containing 99; Coiled-coil domain-containing protein 99; hSpindly; Protein Spindly; Rhabdomyosarcoma antigen MU-RMS-40.4A; rrhabdomyosarcoma antigen protein MU-RMS-40.4A; SPDL1; Spindle apparatus coiled-coil domain-containing protein 1; spindly homolog
Gene Aliases: CCDC99; SPDL1
UniProt ID: (Human) Q96EA4
Entrez Gene ID: (Human) 54908
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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