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Invitrogen
CCK Polyclonal Antibody
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Product Details
PA5-32348
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide within Human Cholecystokinin aa 50 to the C-terminus (N terminal).
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.6, with 1% BSA
Contains
0.1% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2549819
Product Specific Information
Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is stomach tissue.
Target Information
Cholecystokinin (CCK) is a neuropeptide hormone and neurotransmitter widely distributed throughout the gastrointestinal (GI) tract and the central nervous system (CNS). Antibodies that react specifically with CCK are useful for the study of the mode of action, differential tissue expression and intracellular and subcellular localization of CCK in the CNS and periphery as well as in neuroendocrine cells of the digestive system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CCK; Cholecystokinin; cholecystokinin octapeptide; cholecystokinin triacontatriapeptide; prepro-cholecystokinin
Gene Aliases: CCK
UniProt ID: (Human) P06307
Entrez Gene ID: (Human) 885
behavioral fear response
neuron migration
release of cytochrome c from mitochondria
activation of cysteine-type endopeptidase activity involved in apoptotic process
signal transduction
protein kinase C-activating G-protein coupled receptor signaling pathway
axonogenesis
positive regulation of cell proliferation
positive regulation of glutamate secretion
negative regulation of appetite
positive regulation of protein oligomerization
eating behavior
positive regulation of peptidyl-tyrosine phosphorylation
positive regulation of mitochondrial depolarization
regulation of sensory perception of pain
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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