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Product Details
PA5-18609
Product Specifications
Species Reactivity
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (KFDASQKKSAKEKR) corresponding to the internal amino acids of Cckar (aa 256-266).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10986866
Product Specific Information
This antibody is predicted to react with mouse and rabbit based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
This gene encodes a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin family of peptide hormones. This receptor is a major physiologic mediator of pancreatic enzyme secretion and smooth muscle contraction of the gallbladder and stomach. In the central and peripheral nervous system this receptor regulates satiety and the release of beta-endorphin and dopamine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CCK-A receptor; CCK1-R; ccka receptor; Cholecystokinin receptor type A; Cholecystokinin-1 receptor; HGNC:1570
Gene Aliases: Cck-ar; Cckar
UniProt ID: (Rat) P30551
Entrez Gene ID: (Rat) 24889
temperature homeostasis
gastric acid secretion
neuron migration
reduction of food intake in response to dietary excess
positive regulation of cytosolic calcium ion concentration
axonogenesis
response to nutrient
feeding behavior
response to radiation
response to heat
insulin secretion
pancreatic juice secretion
forebrain development
pancreas development
organ regeneration
actin cytoskeleton reorganization
response to lipopolysaccharide
cellular response to hormone stimulus
cholecystokinin signaling pathway
response to starvation
eating behavior
regulation of potassium ion transport
regulation of hormone secretion
response to steroid hormone
response to glucocorticoid
regulation of calcium ion transport
positive regulation of somatostatin secretion
response to peptide
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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